Klebsiella pneumoniae Septic Arthritis in a Cirrhotic Patient with Hepatocellular Carcinoma

نویسندگان

  • Chang Hwan Park
  • Young Eun Joo
  • Sung Kyu Choi
  • Jong Sun Rew
  • Sei Jong Kim
چکیده

Despite septic arthritis is increasingly being reported in elderly patients with diabetes or alcoholism, reported cases of spontaneous bacterial arthritis in cirrhotic patients are extremely rare. We present the first reported case of K. pneumoniae septic arthritis and spontaneous bacterial peritonitis in a cirrhotic patient with hepatocellular carcinoma. K. pneumoniae, one of the most common causative organisms of spontaneous bacterial peritonitis in cirrhotic patients, was isolated from both the blood and the joint fluid, which suggests that the route of infection was hematogenous. After the treatment with cefotaxime and closed tube drainage, the condition of the patient was improved, and subsequently, the joint fluid became sterile and the blood cultures were proved negative. Therefore, this case provides further evidence for the mode of infection being bacteremia in cirrhotic patients and suggests that the enteric bacteremia in cirrhotics may cause infection in different organ systems.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Early Klebsiella pneumoniae Liver Abscesses associated with Pylephlebitis Mimic Hepatocellular Carcinoma

We report on a 57-year-old man with chronic hepatitis B and type 2 diabetes mellitus who developed capsular serotype K1 Klebsiella pneumoniae liver abscesses, which were accompanied by pylephlebitis and the rapid development of septic pulmonary emboli. Because the early stage liver abscesses with pylephlebitis were radiographically-indistinguishable from hepatocellular carcinoma with portal vei...

متن کامل

Septic monoarthritis and osteomyelitis in an elderly man following Klebsiella pneumoniae genitourinary infection: case report.

INTRODUCTION Klebsiella pneumoniae septic arthritis and osteomyelitis, albeit uncommon in adults, are important sites of disseminated infection. Many case reports have shown K. pneumoniae as a cause of nosocomial transmitted septic arthritis in neonates and children. We report a rare case of an elderly patient with K. pneumoniae genitourinary infection spreading to the liver and other extra hep...

متن کامل

DISCRIMINATION OF HEPATOCELLULAR CARCINOMA FROM CIRRHOTIC NODULES BY AgNOR STAIN

Discrimination of regenerative cirrhotic nodules of the liver (CN) from hepatocellular carcinoma (HCC) is sometimes difficult. We examined the utility of AgNOR staining in this context. Fifteen cases of HCC and 25 cases of CN were stained by AgNOR method and the mean AgNOR number for one hundred nuclei in each case was determined. There was a significant difference between the mean AgNOR c...

متن کامل

Septic arthritis subsequent to urosepsis caused by hypermucoviscous Klebsiella pneumoniae.

We herein report the first case of septic arthritis caused by rmpA-positive hypermucoviscous community-acquired K. pneumoniae that followed urosepsis in a 65-year-old Japanese woman. The patient responded well to drainage of the abscesses and treatment with cefazolin. Although this virulent phenotype of K. pneumoniae has been primarily reported in Hong Kong, we confirmed that 18/50 isolates obt...

متن کامل

Septic arthritis in neonates due to Extended Spectrum ß-Lactamase producing Klebsiella pneumoniae - Outbreak analysis and long term follow-up

Between May and June 2002, we recorded an outbreak of Septic Arthritis in neonates due to Extended Spectrum ß-Lactamase producing Klebsiella pneumoniae at our neonatal intensive care unit. The confirmed cases were then followed up to look for long term morbidities associated with the infection. We analyzed the microbiological and epidemiological features of the outbreak and the various measures...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 19  شماره 

صفحات  -

تاریخ انتشار 2004